Transfusion is commonly used in the clinical treatment. Due to the frequent interaction during transfusion, operation and continuous liquid are of great importance besides liquid and medicine itself .As to the protection of clinical liquid medicine bottle opening; it is strict required in sterile technique operation. To maintain the sealing surface in an sterile status, iodine cotton swab, alcohol cotton swab and cotton bud are widely used to cover the bottle opening at present. Because of its not fixed sealing or even shedding, it will increase possibility of liquid medicine contamination. And also the current bottle sealing is not easy to be stripped and consequently affect use efficiency. Therefore, our company develops a new sterile bottle sealing with easy stripping and great convenience.